| 耿春松,曾万杰,樊一笋,等.过敏性疾病患者血清特异性免疫球蛋白E检测分析[J].安徽医药,2018,22(11):2144-2146. |
| 过敏性疾病患者血清特异性免疫球蛋白E检测分析 |
| Detection and analysis of serum sIgE in patients with allergic diseases |
| 投稿时间：2017-04-23 |
| DOI： |
| 中文关键词: 过敏原 特异性免疫球蛋白E 体外检测 |
| 英文关键词: Allergen Specific immunoglobulin E In vitro assay |
| 基金项目: |
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| 中文摘要: |
| 目的 通过检测过敏性疾病患者血清特异性免疫球蛋白E(sIgE)水平,了解该地区过敏性疾病患者的过敏原分布特征,为临床诊断和治疗过敏性疾病提供理论依据。方法 选取2013年7月至2015年7月在苏州九龙医院就诊的171例过敏性疾病患者,采用Allergy Screen过敏原定量检测系统对171例过敏性疾病患者血液进行吸入性和食入性过敏原sIgE检测。结果10种吸入性过敏原中位居前5位的是户尘螨、混合真菌、狗毛皮屑、猫毛皮屑、屋尘,阳性率分别为40.54%、19.82%、10.81%、7.21%和7.21%；9种食入性过敏原中位居前5位的是牛奶、鸡蛋白、牛肉、腰果和蟹,阳性率分别为29.94%、21.47%、16.95%、10.17%和9.04%。吸入性过敏原血清sIgE总阳性率(55.64%)高于食入性过敏原(44.36%),差异有统计学意义(χ2=8.581,P＜0.05)。结论 引起过敏性疾病的过敏原种类众多,吸入性过敏原发病率高于食入性过敏原,过敏原的确定对过敏性疾病的治疗及预防具有重要作用。 |
| 英文摘要: |
| Objective To investigate the distribution of allergens in patients with allergic diseases by detecting the level of specific immunoglobulin E (sIgE) in patients with allergic diseases,and to provide a basis for clinical diagnosis and treatment of allergic diseases.Methods One hundred and seventy-one patients with allergic diseases in Suzhou Kowloon Hospital from July 2013 to July 2015 were selected.Allergy screen allergen quantitative detection system was used to detect the sIgE in inhalant and food allergens in 171 patients with allergic diseases.Results Among the 10 kinds of inhalant allergens,dust mite,fungi,dog dander,mixed cat dander and house dust ranked top-five;the positive rates were 40.54%,19.82%,10.81%,7.21% and 7.21%,respectively.Among the 9 kinds of food allergens,milk,egg white,beef,cashew nuts and crab ranked top-five;the positive rates were 29.94%,21.47%,16.95%,10.17% and 9.04%,respectively.The positive rate of sIgE in the serum of the inhalant allergens(55.64%) was significantly higher than that in food allergens(44.36%) (χ2=8.581,P<0.05).Conclusion There are many allergens causing allergic diseases,the incidence of inhalant allergens is higher than that of food allergens,and the determination of allergens has a good guiding significance for the diagnosis and prevention of allergic diseases. |
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