| 张典云,夏昕.血清淀粉样蛋白A与甲状旁腺激素联合检测在血透病人中的应用[J].安徽医药,2019,23(2):293-295. |
| 血清淀粉样蛋白A与甲状旁腺激素联合检测在血透病人中的应用 |
| Application of combined detection of serum amyloid Aand parathyroid hormone in hemodialysis patients |
| 投稿时间：2017-08-29 |
| DOI： |
| 中文关键词: 血清淀粉样蛋白A 甲状旁腺素 血透 |
| 英文关键词: Serum amyloid A Parathyroid hormone Hemodialysis |
| 基金项目: |
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| 中文摘要: |
| 目的 探讨血清淀粉样蛋白A与甲状旁腺激素在监测血透病人感染、激素代谢紊乱中的应用价值。方法 收集2014年9月至2016年11月在合肥市第一人民医院就诊的50例血透病人作为血透组,20例正常体检者作为对照组,并对血清淀粉样蛋白A、甲状旁腺激素等相关指标进行检测,比较两组检测结果的差异；同时根据血透时间的长短,分为≤6个月组和>6个月组,比较两组上述各检测结果的差异,并进行统计学分析。结果 血透组和对照组的血清淀粉样蛋白A[(37.57±19.35) mg/L比(11.23±5.41)mg/L]、甲状旁腺激素[(380.05±135.94) pg/mL比(55.12±8.24) pg/mL]、C-反应蛋白[(7.83±2.27) mg/L比(3.48±1.10) mg/L]、磷[(1.89±0.59) mmol/L比(1.30±0.15) mmol/L]等指标比较,差异有统计学意义(t=5.971、10.635、 8.169、4.398,均P=0.000)；血透病人中≤6个月组和>6个月组仅有血清淀粉样蛋白A[(10.98±3.79) mg/L比(60.21±14.41) mg/L]、甲状旁腺激素[(334.33±23.81) pg/mL比(419.00±136.72) pg/mL]和C-反应蛋白[(5.30±1.71) mg/L比(9.99±10.78) mg/L]差异有统计学意义(t=15.900、 2.928、 2.062,P=0.000、0.005、 0.045)。结论 血清淀粉样蛋白A和甲状旁腺激素可作为血透病人感染、激素代谢紊乱的重要监测指标。 |
| 英文摘要: |
| Objective To investigate the application value of serum amyloid Aand parathyroid hormone in monitoring infection and hormone metabolism disorder of hemodialysis patients.Methods A total of 50 hemodialysis patients in The First People's Hospital of Hefei from September 2014 to November 2016 were collected as hemodialysis group,and another 20 healthy people were chosen as healthy control group.The serum amyloid Aand parathyroid hormone were examined,and the differences between the two groups were compared and analyzed.Meanwhile,the patients were assigned into ≤6 months group and >6 months group according to the duration of hemodialysis.The differences between the two groups were compared and statistically analyzed.Results The levels of serum amyloid A[(37.57±19.35) mg/L vs.(11.23±5.41) mg/L],parathyroid hormone [(380.05±135.94) pg/mL vs.(55.12±8.24) pg/mL],C-reactive protein [(7.83±2.27) mg/L vs.(3.48±1.10) mg/L] and phosphorus [(1.89±0.59) mmol/L vs.(1.30±0.15) mmol/L] were significantly different between hemodialysis group and healthy control group (t=5.971,0.635,8.169,4.398;P=0.000,0.000,0.000,0.000);the levels of serum amyloid A [(10.98±3.79) mg/L vs.(60.21±14.41) mg/L],parathyroid homone [(334.33±23.81) pg/mL vs.(419.00±136.72) pg/mL] and C-reactive protein [(5.30±1.71) mg/L vs.(9.99±10.78) mg/L] were significantly different between ≤6 months group and >6 months group (t=15.900,2.928,2.062;P=0.000,0.005,0.045).Conclusions The level of serum amyloid Aand parathyroid hormone could be used as important monitoring indicators of infection and hormone metabolism disorder in hemodialysis patients. |
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