| 王欣,王子瑞.机采血小板对献血者血常规参数的影响[J].安徽医药,2019,23(5):981-983. |
| 机采血小板对献血者血常规参数的影响 |
| Effect of mechanical platelet collection on blood routine parameters of blood donors |
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| DOI：10.3969/j.issn.1009-6469.2019.05.039 |
| 中文关键词: 血小板去除法 供血者 血小板计数 红细胞计数 白细胞计数 血红蛋白类 血细胞比容 |
| 英文关键词: Plateletpheresis Blood donors Platelet count Erythrocyte count Leukocyte count Hemoglobins Hematocrit |
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| 中文摘要: |
| 目的 监测机采血小板献血者的血常规参数变化,评估捐献血小板、2周机采间隔及多次机采血小板对献血者健康状况的影响。方法 分别检测献血者血小板捐献单份前后、双份前后、间隔2周再次捐献前、7个月内连续捐献血小板10次献血者的首次和末次捐献前血常规参数,并进行对比分析。结果 28例机采单份血小板献血者采集前、后WBC浓度差异无统计学意义(t＝-1.911＜t0.025(19)＝2.093,P＞0.05);40例机采双份血小板献血者采集前、后WBC浓度差异无统计学意义(t＝-2.016＜t0.025(39)＝2.023,P＞0.05)。而20例间隔2周机采血小板献血者两次采集前白细胞计数、红细胞计数、血红蛋白、血细胞比容、血小板计数［前一次机采前:WBC(6.13±1.54)×109/L、RBC(4.81±0.38)×1012/L、HB(144.70±10.53)g/L、HCT(42.11±3.36)%、PLT(265.45±39.37)×109/L;2周后机采前:WBC(6.21±1.46)×109/L、RBC(4.78±0.41)×1012/L、HB(141.90±11.81)g/L、HCT(43.09±3.32)%、PLT(266.15±40.24)×109/L］比较,差异无统计学意义(P＞0.05)。另20例7个月内连续10次机采血小板献血者首次和末次采集前WBC、RBC、HB、HCT、PLT［首次机采前:WBC(6.28±1.41)×109/L、RBC(4.93±0.37)×1012/L、HB(147.30±9.31)g/L、HCT(42.11±3.64)%、PLT(262.35±41.48)×109/L;末次机采前:WBC(6.22±1.34)×109/L、RBC(4.87±0.36)×1012/L、HB(144.80±9.17)g/L、HCT(41.67±2.98)%、PLT(266.80±46.93)×109/L］比较,亦差异无统计学意义(P＞0.05)。结论 机采血小板对献血者是安全的,2周的采集间隔和多次反复机采血小板不影响献血者健康状况。 |
| 英文摘要: |
| Objective To monitor changes in blood routine parameters of apheresis platelet donors,and to evaluate the effects of donating platelets,two-week interval apheresis collections,and multiple apheresis collections on the health status of blood donors.Methods The blood routine parameters of the blood donors before and after the single apheresis platelets,before and after the double apheresis platelets,before the second time donation in two-week intervals,and before the first and last time donation of donors with ten consecutive platelets donation within seven months were compared and analyzed.Results There was no significant difference in white blood cell count before and after collection in 28 patients with single platelet donor(t＝-1.911＜t0.025(19)＝2.093,P＞0.05);There was no significant difference in white blood cell count before and after the double platelet donor in 40 cases(t＝-2.016＜t0.025(39)＝2.023,P＞0.05)。In 20 cases,platelets were collected twice in a row,two weeks apart.There was no significant difference in white blood cell count,red blood cell count,hemoglobin,hematocrit and platelet count before the two collections.(Before the previous collection WBC(6.13±1.54)×109/L,RBC(4.81±0.38)×1012/L,HB(144.70±10.53)g/L,HCT(42.11±3.36)%,PLT(265.45±39.37)×109/L;Two weeks before the collection:WBC(6.21±1.46)×109/L,RBC(4.78±0.41)×1012/L,HB(141.90±11.81)g/L,HCT(43.09±3.32)%,PLT(266.15±40.24)×109/L)In the other 20 cases,there was no statistically significant difference between the first and last precollection white blood cell count,red blood cell count,hemoglobin,red blood cell accretion,and platelet count in 10 consecutive platelet donors within 7 months.(Before the first collection WBC(6.28±1.41)×109/L,RBC(4.93±0.37)×1012/L,HB(147.30±9.31)g/L,HCT(42.11±3.64)%,PLT(262.35±41.48)×109/L;Before the last collection:WBC(6.22±1.34)×109/L,RBC(4.87±0.36)×1012/L,HB(144.80±9.17)g/L,HCT(41.67±2.98)%,PLT(266.80±46.93)×109/L) Conclusion Apheresis platelet is safe for blood donors.The two-week interval apheresis collections and repeated apheresis collections do not affect the health status of blood donors. |
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