文章摘要
袁庆芳,李欣欣.颈内动脉闭塞的脑梗死病人侧支循环与近期预后的相关分析[J].安徽医药,2019,23(11):2227-2230.
颈内动脉闭塞的脑梗死病人侧支循环与近期预后的相关分析
Correlation of collateral circulation with short?term prognosis in cerebral infarction with internal carotid artery occlusion
  
DOI:10.3969/j.issn.1009?6469.2019.11.027
中文关键词: 颈动脉狭窄  脑梗死  侧支循环  预后
英文关键词: Carotid stenosis  Brain infarction  Collateral circulation  Prognosis
基金项目:
作者单位
袁庆芳 无锡市人民医院神经内科江苏无锡 214023 
李欣欣 无锡市人民医院神经内科江苏无锡 214023 
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中文摘要:
      目的探讨颈内动脉闭塞( ICAO)的脑梗死病人侧支循环的建立情况,及其与近期预后的相关性。方法选取 2014年 1月至 2016年 6月无锡市人民医院收治的 ICAO脑梗死病人 72例,根据脑梗死病灶数量分为单发脑梗死组 29例、多发脑梗死组 43例,比较两组侧支循环建立数量及分级。采用美国国立卒中量表( NIHSS)评估入院时、入院后 2周的脑神经功能,分析侧支循环对病人近期预后的影响。结果单发脑梗死病人侧支循环开放数量 ≥2支( 79.3%)及一级侧支循环开放的比例( 93.1%)较多发脑梗死组明显增多( 55.8%、74.4%)(P<0.05);合并侧支循环组病人入院时( 4.14±0.84)分、入院后 2周 NHISS评分( 0.94±0.32)分与未合并侧支循环组[(5.18±1.27)、(2.36±0.66)分]比较,显著降低,而 NHISS评分降幅显著升高( P<0.05); Willis环开放组病人入院时( 4.05±0.65)分、入院后 2周 NHISS评分( 0.87±0.30)较 Willis环未开放组明显降低[( 5.31±1.34)、(2.47± 0.73)分]而 NHISS评分降幅更为明显( P<0.05)。结论 ICAO病人脑梗死类型与侧支循环形成数量和分级密切相关,侧支循环形成尤其,是一级侧支循环( Willis环)的开放可有效改善近期临床预后。
英文摘要:
      Objective To explore the establishment of collateral circulation in cerebral infarction with internal carotid artery occlu? sion(ICAO), and analyze its correlation with short?term prognosis.Methods 72 patients with internal carotid artery occlusion(ICAO)were selected in Wuxi People’s Hospital from 2014.1 to 2016.6. The number and grade of collateral circulation establish?ment between two groups were compared.National Institutes of Health Stroke Scale(NIHSS)was used to assess the cerebral nerve function on admission,2 weeks after admission,to analyze the effect of collateral circulation on the short?term prognosis. Results The proportions of number of collateral circulation more than 2(79.3% vs. 55.8%)and primary collateral circulation in single cerebral infarction group(93.1% vs. 74.4%)was increased significantly in multiple cerebral infarction group(P<0.05).Com? pared with non collateral circulation group,the NHISS scores on admission[( 4.14±0.84)vs.(5.18±1.27)],2 weeks after admis? sion[( 0.94±0.32)vs.(2.36±0.66)] in collateral circulation group were decreased significantly,while decline of NHISS score was significantly increased(P<0.05); Compared with non Willis circle group,the NHISS scores on admission[(4.05±0.65)vs.(5.31±
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