文章摘要
李秀芹.超声造影对甲状腺乳头状癌和颈部淋巴结转移的诊断价值[J].安徽医药,2020,24(3):508-511.
超声造影对甲状腺乳头状癌和颈部淋巴结转移的诊断价值
Diagnostic value of contrast?enhanced ultrasound in papillary thyroid carcinoma and cervical lymph node metastasis
  
DOI:10.3969/j.issn.1009?6469.2020.03.022
中文关键词: 甲状腺肿瘤/诊断  淋巴转移  超声检查,多普勒,彩色  诊断,鉴别  注射用六氟化硫微泡
英文关键词: Thyroid neoplasms/diagnosis  Lymphatic metastasis  Ultrasonography,doppler,color  Diagnosis,differential  Microvesicle sulfur hexafluoride for injection
基金项目:
作者单位
李秀芹 河南省中医药研究院附属医院影像科河南郑州 450000 
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中文摘要:
      目的探讨超声造影对甲状腺乳头状癌( PTC)及颈部淋巴结转移的诊断价值。方法选取 2015年 12月至 2018年 12月河南省中医药研究院附属医院收治的行甲状腺结节切除病人 90例( 90个结节)为研究对象,病人均经超声造影及术后病理学检查。以术后病理学检查结果为金标准,分析超声造影区分 PTC结节及良性结节价值及评估颈部淋巴结转移的价值。结果 90例经术后病理学检查, 62例确诊为 PTC,其中 21例伴有颈部淋巴结转移; PTC结节达峰时间( TTP)大于良性结节,峰值强度(PI)小于良性结节,均差异有统计学意义( P<0.05);超声造影 PTC结节及良性结节的灵敏度为 96.77%,特异度为 96.43%,准确率为 96.67%;淋巴结转移阳性者、淋巴结转移阴性者间增强程度及 PI比较,差异有统计学意义( P<0.05);超声造影等高增强诊断颈淋巴结转移灵敏度 61.90%,特异度 75.60%。PI参数诊断颈淋巴结转移灵敏度 81.00%,特异度 78.00%。结论 PTC结节与良性结节、颈部淋巴结转移与未转移病人超声造影表现具有一定差异;超声造影不仅能够区别结节良恶性,还可预测颈部淋巴结转移,为手术术式选择提供参考。
英文摘要:
      Objective To investigate the diagnostic value of contrast?enhanced ultrasound in papillary thyroid carcinoma(PTC) and cervical lymph node metastasis.Methods A total of 90 patients(90 nodules)who underwent thyroid nodule resection in theAffiliated Hospital of Henan Chinese Medicine Research Institute from December 2015 to December 2018 were selected for thestudy.All patients were given contrast?enhanced ultrasound and postoperative pathological examination.Taking the results of postop?erative pathological examination as golden standards,the diagnostic value of contrast?enhanced ultrasound in PTC and cervical lymph node metastasis was analyzed.Results In the 90 cases examined by postoperative pathology,there were 62 cases with PTC, including 21 cases combined with cervical lymph node metastasis.The time to peak(TTP)of PTC nodules was greater than that of benign nodules while the peak intensity(PI)was less than that of benign nodules(P<0.05).The sensitivity,specificity and accura? cy rate of contrast?enhanced ultrasound in the diagnosis of PTC nodules and benign nodules were 96.77%,96.43% and 96.67%,re? spectively.There were significant differences in enhancement degree and PI index between patients with positive lymph node metas?tasis and patients with negative lymph node metastasis(P<0.05).The sensitivity and specificity of contrast?enhanced ultrasound inthe diagnosis of cervical lymph node metastasis were 61.90% and 75.60%,respectively.The sensitivity and specificity of PI parame?ter in the diagnosis of cervical lymph node metastasis were 81.00% and 78.00%,respectively.Conclusions There are certain dif? ferences in the findings of contrast?enhanced ultrasound between PTC nodules and benign nodules and between patients with orwithout cervical lymph node metastasis.Contrast?enhanced ultrasound can not only distinguish between benign and malignant nod?ules,but also predict cervical lymph node metastasis,and it provides a reference for surgical procedures.
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