| 张倩倩,张体华,周玫娟,等.核磁共振检查视神经脊髓炎 30例影像特征分析[J].安徽医药,2020,24(8):1534-1536. |
| 核磁共振检查视神经脊髓炎 30例影像特征分析 |
| Analysis of imaging characteristics of 30 patients with optic neuromyelitis by MRI |
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| DOI：10.3969/j.issn.1009?6469.2020.08.013 |
| 中文关键词: 视神经脊髓炎 磁共振成像 脱髓鞘 水通道蛋白质 4 |
| 英文关键词: Neuromyelitis optica Magnetic resonance imaging Demyelination Aquaporin 4 |
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| 中文摘要: |
| 目的分析视神经脊髓炎(neuromyelitis optica，NMO)MRI影像学特点。方法回顾分析 2009年 2月至 2018年 9月开封市中心医院收治的视神经脊髓炎病人 30例，采用 1.5T MR扫描仪对病人行头颅及脊髓核磁共振(MRI)检查，分析病人脑部病灶、脊髓病灶及视神经病灶的分布特点。结果 30例 NMO病人女性多于男性，约 9∶1；30例病人的 MRI检查中出现脑部病变 25例。病变主要位于水通道蛋白质 4(AQP?4)高表达区及大脑白质区等处，病灶多呈斑点、斑片状，大部分对称分布，部分病灶融合成片状。脊髓 MRI异常 24例，主要累及颈髓、胸髓，表现为多于 3个椎体节段的连续性、对称性病灶。视神经 MRl异常 11例，主要累及视神经后段，常双侧受累，病灶节段长度大部分大于 1/2视神经。颅脑增强表现云雾样及薄线样强化，脊髓病灶呈点状、小斑片状、线条状及环形均匀或不均匀强化，视神经呈轻度强化。结论 MRI检查为视神经脊髓炎诊断提供了可靠依据。 |
| 英文摘要: |
| Objective To analyze imaging features of MRI in neuromyelitis optica(NMO).Methods Thirty patients with opticneuritis treated in Kaifeng Central Hospital from February 2009 to September 2018 were retrospectively analyzed and performedwith a 1.5T MR scanner to examine the head and spinal cord magnetic resonance imaging(MRI).The patient’s brain lesions，spi? nal cord lesions and optic nerve lesions distribution characteristics were analyzed.Results There were more women than men in 30 cases of NMO，about 9:1.In 30 patients，25 cases of brain lesions occurred in MRI examination.The lesions were mainly locatedin the high expression area of AQP?4 and the white matter area of the brain，and the lesions were mostly spotted and patchy，most of them were symmetrical，and some of the lesions fused into patches.MRI abnormalities in the spinal cord were 24 cases，mainly in? volving the cervical medulla and thoracic pulp，and showed the continuity and symmetrical long lesions of more than 3 vertebraesegments.11 cases of optic nerve MRI abnormalities，mainly involved in the posterior segment of the optic nerve，often bilateral in? volvement，the length of the lesion segment is greater than 1/2 optic nerve.Craniocerebral enhancement showed cloudy sample andthin line?like enhancement，spinal cord lesions showed point，small patches，lines and annular uniform or uneven enhancement，the optic nerve showed mild enhancement.Conclusion MRI examination provides a reliable basis for diagnosis of optic myelitis. |
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