文章摘要
罗丽芳,阮军谊,李桂梅.经脐单孔腹腔镜手术与多孔腹腔镜手术对妇科良性疾病的炎性因子、疼痛程度的影响[J].安徽医药,2020,24(11):2221-2224.
经脐单孔腹腔镜手术与多孔腹腔镜手术对妇科良性疾病的炎性因子、疼痛程度的影响
Effects of transumbilical single?port laparoscopic surgery and porous laparoscopic surgery on inflammatory factors and pain in patients with gynecological benign diseases
  
DOI:10.3969/j.issn.1009?6469.2020.11.026
中文关键词: 妇科外科手术  腹腔镜手术  妇科良性疾病  炎性因子  疼痛
英文关键词: Gynecologic surgical procedures  Laparoscopic surgery  Gynecological benign diseases  Inflammatory factors  Pain
基金项目:
作者单位
罗丽芳 惠州市第六人民医院妇科广东惠州 516200 
阮军谊 惠州市第六人民医院妇科广东惠州 516200 
李桂梅 惠州市第六人民医院妇科广东惠州 516200 
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中文摘要:
      目的对比分析经脐单孔腹腔镜手术(LESS)与多孔腹腔镜手术在妇科良性疾病中的应用效果。方法选取 2016年 8月至 2018年 2月惠州市第六人民医院收治的妇科良性疾病病人 118例,根据不同手术方法分为 A组 59例, B组 59例, A组行 LESS术, B组行多孔腹腔镜手术,对比两组手术效果、手术相关指标、炎性因子、疼痛程度及并发症情况。结果手术成功率 A组为 96.61%,B组为 98.31%,中转开腹率 A组为 3.39%,B组中为 1.69%,差异无统计学意义(P>0.05); A组手术时间(45.37±5.37)min,B组手术时间(22.04±4.89)min,A组长于 B组(P<0.05)两组术中出血量、术后排气时间、首次下床时间、住院时间比较,差异无统计学意义(P>0.05);两组术前 C反应蛋白(CRP)、,白介素 ?1(IL?1)、白介素 ?6(IL?6)比较,差异无统计学意义(P>0.05),A组术后 3d上述指标水平明显低于同期 B组(P<0.05); A组术后 1d、3d视觉模拟评分(VAS)(2.24±0.35)、(1.01±0.07)分, B组术后 1d、3 d VAS(3.17±0.43)、(1.49±0.24)分,均 A组低于 B组(P<0.05)A组止痛药使用频率低于 B组[(1.34±0.58)比(1.73±0.63)次, P<0.05];两组并发症发生率 A组为 1.69%,B组为 3.39%。差统计学意义(P>0.05)。结论 LESS异无,术与多孔腹腔镜手术在妇科良性疾病中手术效果相当,但 LESS术后炎症反应及疼痛程度更轻,更值得推广。
英文摘要:
      Objective To compare and analyze the effects of transumbilical single?port laparoscopic surgery(LESS)and porous laparoscopic surgery in gynecological benign diseases.Methods A total of 118 patients with gynecological benign diseases admit? ted to the Sixth People’s Hospital of Huizhou from August 2016 to February 2018 were selected.According to different surgical methods,they were divided into group A(59 cases)and group B(59 cases).Group A underwent LESS and group B underwent po? rous laparoscopic surgery.The operative effects,operative related indicators,inflammatory factors,pain degree and complications were compared between the two groups.Results The success rate of operation was 96.61% in group A and 98.31% in group B, and the conversion to laparotomy rate was 3.39% in group A and 1.69% in group B,with no significant difference(P>0.05); The operation time in group A was significantly longer than that in group B[(45.37±5.37)min vs.(22.04±4.89)min,P<0.05],and there was no significant difference in intraoperative bleeding volume,postoperative exhaust time,first time out of bed and hospital? ization time between the two groups(P>0.05).There was no significant difference in C?reactive protein(CRP),interleukin?1(IL?1)and interleukin?6(IL?6)between the two groups before operation(P>0.05).The above?mentioned indexes in group A were sig? nificantly lower than those in group B on the 3rd day after operation(P<0.05); The visual analogue score(VAS)and the frequen? cy of analgesic use in group A on the 1st day[(2.24±0.35)vs.(3.17±0.43)]and 3rd day[(1.01±0.07)vs.(1.49±0.24)]after oper? ation were significantly lower than those in group B[(1.34±0.58)vs.(1.73±0.63),P<0.05],and the frequency of analgesic use in group A after operation were significantly lower than those in group B(P<0.05); The incidence of complications was 1.69% in group A and 3.39% in group B.There was no significant difference(P>0.05).Conclusion LESS and porous laparoscopic surgery have the same effect on gynecological benign diseases,but the degree of inflammation and pain after LESS is lighter,which is worth popularizing.
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