| 杨航,张红.肺泡 Ⅱ型上皮细胞与肺部疾病的研究进展[J].安徽医药,2021,25(2):217-221. |
| 肺泡 Ⅱ型上皮细胞与肺部疾病的研究进展 |
| Research progress of alveolar type Ⅱ epithelial cells and lung diseases |
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| DOI：10.3969/j.issn.1009-6469.2021.02.002. |
| 中文关键词: 肺泡上皮细胞 肺组织损伤 肺部疾病 |
| 英文关键词: Alveolar type epithelial cells Lung tissue damage Lung diseases |
| 基金项目:国家自然科学基金( 81760079)；贵州省麻醉学研究生工作站资助项目(黔教研合 GZZ字-2016-05) |
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| 中文摘要: |
| 肺泡上皮细胞主要由肺泡 Ⅰ型上皮细胞和肺泡 Ⅱ型上皮细胞组成，但肺泡 Ⅱ型上皮细胞在维持正常肺功能有着更为重要的作用，如维持屏障功能完整、再生功能、分泌功能等；同时其与肺部疾病的发生发展有密切关系。该文对肺泡 Ⅱ型上皮细胞的正常生理功能，及其在急性肺损伤、间质性肺疾病、肺部肿瘤、肺结核、慢性阻塞性肺疾病等肺部疾病的研究进展作一综述。 |
| 英文摘要: |
| Alveolar epithelial cells are mainly composed of alveolar type Ⅰ epithelial cells and alveolar type Ⅱ epithelial cells, butalveolar type Ⅱ epithelial cells have more important functions in maintaining normal lung function, such as maintaining the integrity ofbarrier functions, regeneration functions, and secretory functions.It is closely related to the occurrence and development of lung diseases.This article reviews the normal physiological functions of alveolar type Ⅱ epithelial cells and their research progress in lung diseases such as acute lung injury, interstitial lung disease, lung tumors,tuberculosis, and chronic obstructive pulmonary disease. |
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