文章摘要
沈光贵,仲昌顺,袁荆,等.高流量鼻导管氧疗与无创通气在拔管后呼吸衰竭中的应用比较[J].安徽医药,2021,25(2):292-295.
高流量鼻导管氧疗与无创通气在拔管后呼吸衰竭中的应用比较
Comparison of high-flow nasal cannula oxygen therapy and non-invasive ventilation on respiratory failure after endotracheal extubation
  
DOI:10.3969/j.issn.1009-6469.2021.02.020.
中文关键词: 呼吸衰竭  气管插管拔除  无创通气  高流量鼻导管氧疗
英文关键词: Respiratory failure  Airway extubation  Noninvasive ventilation  High-flow nasal cannula
基金项目:安徽省中央引导地方科技发展专项项目( 201907d07050001);重大疾病非编码 RNA转化研究安徽普通高校重点实验室开放课题( RNA201910)
作者单位E-mail
沈光贵 皖南医学院弋矶山医院重症医学科安徽芜湖 241000  
仲昌顺 皖南医学院弋矶山医院重症医学科安徽芜湖 241000  
袁荆 皖南医学院弋矶山医院重症医学科安徽芜湖 241000  
陈群 皖南医学院弋矶山医院重症医学科安徽芜湖 241000  
秦雪梅 皖南医学院弋矶山医院重症医学科安徽芜湖 241000  
鲁卫华 皖南医学院弋矶山医院重症医学科安徽芜湖 241000  
王箴 皖南医学院弋矶山医院重症医学科安徽芜湖 241000 zhenwang80@126.com 
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中文摘要:
      目的比较高流量鼻导管氧疗与无创通气在拔管后呼吸衰竭中应用的有效性。方法回顾性分析皖南医学院弋矶山医院重症医学科 2017年 11月至 2019年 10月气管拔管后呼吸衰竭病人 77例。按治疗方法分为无创通气治疗组( 41例)及高流量鼻导管氧疗治疗组( 36例)。对比两组在避免气管再插管率、拔管后滞留重症监护室( ICU)时间及病死率等临床指标。结高流量鼻导管氧疗组和无创通气组在避免气管再插管率方面差异无统计学意义( 77.78%比 65.85%,χ2=1.336,P =
英文摘要:
      Objective To compare the effectiveness of high-flow nasal cannula (HFNC) and noninvasive ventilation (NIV) on the patients with respiratory failure after endotracheal extubation.Methods A retrospective study was conducted on 77 patients with respiratory failure after endotracheal extubation in the Department of Critical Care Medicine, Yijishan Hospital, Wannan Medical College fromNovember 2017 to October 2019. 41 patients were treated with noninvasive ventilation, and 36 patients were treated with high-flow nasal catheter. A series of parameters, including the rate of avoiding endotracheal intubation, the length of ICU stay after extubation andmortality, were compared between two groups.Results There are no significant differences between two groups in the following parameters: the rate of avoiding endotracheal intubation (77.78% vs. 65.85%, χ2 = 1.336, P = 0.248), the length of ICU stay after extubation (9.23±6.36 days vs.10.20±8.73 days, t = 0.550,P = 0.584), the mortality in ICU (13.89% vs.14.63%, χ2 = 0.009, P = 0.926) and the hospital mortality (16.67% vs. 17.07%, χ2 = 0.002, P = 0.962).Conclusion HFNC oxygen therapy can replace NIV in the patients with respiratory failure after endotracheal extubation.
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