| 解宝泉,王立民,张静华.血浆纤维蛋白原与血清细胞角蛋白 19片段联合检测在肺栓塞合并肺鳞癌中的临床意义[J].安徽医药,2021,25(5):914-916. |
| 血浆纤维蛋白原与血清细胞角蛋白 19片段联合检测在肺栓塞合并肺鳞癌中的临床意义 |
| Clinical significance of combined detection of FIB and CYFRA21-1 in patients with squa? mous cell carcinoma and pulmonary embolism |
| |
| DOI：10.3969/j.issn.1009-6469.2021.05.016 |
| 中文关键词: 肺栓塞 肺肿瘤 纤维蛋白原 角蛋白细胞 |
| 英文关键词: Pulmonary embolism Lung neoplasms Fibrinogen Keratinocytes |
| 基金项目:河北省 2018年度医学科学研究重点课题( 20180781) |
|
| 摘要点击次数: 1322 |
| 全文下载次数: 537 |
| 中文摘要: |
| 目的探讨血浆纤维蛋白原(FIB)与血清细胞角蛋白 19片段( CYFRA21-1)联合检测在肺栓塞合并肺鳞癌病人中的临床意义。方法选取 2017年 1月至 2018年 10月华北理工大学附属医院收治的肺栓塞病人 150例，分为两组，经活检或手术组织病理证实发生肺鳞癌 30例为肿瘤组，未发生肺鳞癌 120例为对照组。比较两组入院时血浆 FIB及血清 CYFRA21-1水平。结两组 FIB及 CYFRA21-1水平比较，肿瘤组 FIB(5.48±2.34)g/L及 CYFRA21-1(8.68±3.25)ng/mL均明显高于对照组 FIB(3果.58±1.40)g/L及 CYFRA21-1(2.64±1.53)ng/mL，差异有统计学意义( P<0.05)；肿瘤组阳性检出率 FIB(63%)及 CYFRA21-1(83%)明显高于对照组阳性检出率 FIB(16%)及 CYFRA21-1(20%)差异有统计学意义( P<0.05)；肿瘤组 FIB及 CYFRA21-1水平呈正相关(r=0.274，P<0.01)。结论对肺栓塞合并肺鳞癌病人联合，检测 FIB及 CYFRA21-1水平具有指导诊断意义。 |
| 英文摘要: |
| Objective To investigate the clinical significance of combined detection of FIB and CYFRA21-1 in patients with pulmonary embolism and pulmonary squamous cell carcinoma.Methods 150 patients with pulmonary embolism were divided into twogroups in Affiliated Hospital of North China University of Technology form January 2017 to October 2018.30 patients with pulmonarysquamous cell carcinoma were tumor group, and 120 patients without pulmonary squamous cell carcinoma were control group.Results The levels of FIB and CYFRA21-1 in tumor group (5.48 ± 2.34) g / L and CYFRA21-1 (8.68 ± 3.25)ng / mL were significantly higher than those in control group (3.58 ± 1.40)g / L and CYFRA21-1 (2.64 ± 1.53) ng / mL, The difference was statistically significant (P < 0.05); the positive detection rates of FIB (63%) and CYFRA21-1 (83%) in the tumor group were significantly higher than those in the control group (16%) and CYFRA21-1 (20%), the difference was statistically significant (P < 0.05); the levels of FIB and CYFRA21-1 in the tumor group were positively correlated (r = 0.274, P < 0.01).Conclusion The combined detection of FIB and CYFRA21-1 levels in patients with pulmonary embolism with pulmonary squamous cell carcinoma complicated has guiding diagnostic significance. |
|
查看全文
查看/发表评论 下载PDF阅读器 |
| 关闭 |
