文章摘要
汪永宏.乳腺癌化疗 167例的质子泵抑制剂使用合理性分析[J].安徽医药,2021,25(9):1901-1904.
乳腺癌化疗 167例的质子泵抑制剂使用合理性分析
Rationality of using proton pump inhibitors in 167 cases of breast cancer patients undergoing chemotherapy
  
DOI:10.3969/j.issn.1009-6469.2021.09.049
中文关键词: 处方不当  质子泵抑制剂  乳腺肿瘤  化疗病人
英文关键词: Inappropriate prescribing  Proton pump inhibitors  Breast neoplasms  Chemotherapy patients
基金项目:安徽省“十三五”医疗卫生重点专科建设项目(皖卫科教〔 2017〕30号)
作者单位
汪永宏 安徽医科大学第三附属医院、合肥市第一人民医院药学部安徽合肥 230061 
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中文摘要:
      目的分析乳腺癌化疗病人质子泵抑制剂使用的合理性, 9为临床乳腺癌化疗病人规范使用质子泵抑制剂提供参考。方法收集 2018年 6月至 2019年 5月合肥市第一人民医院乳腺癌化疗病人 167例,通过回顾性调查分析,对质子泵抑制剂使用情况进行统计,依据指南对其分析。结果 167例病例中, 134例使用了质子泵抑制剂,适应证不适宜 101例,用法用量不适宜 109例,其它不适宜 2例。结论该院乳腺癌化疗病例质子泵抑制剂的无指征使用和用法用量不适宜现象较多。建议该院采取整改措施,通过多部门联动,实施用药干预,规范质子泵抑制剂在乳腺癌化疗病人中的应用。
英文摘要:
      Objective To analyze the rationality of using proton pump inhibitors (PPIs) in breast cancer patients treated with chemotherapy and provide references for the standard use of.Methods A hundred and sixty-seven cases of breast cancer patients undergoing chemotherapy in The First People's Hospital of Hefei from June 2018 to May 2019 were collected. The use of PPIs in these caseswas counted and analyzed retrospectively based on the practice guidelines.Results Of the 167 cases, there were 134 cases treatedwith PPIs, and mismatched indications were found in 101 cases, inappropriate usage and dosage in 109 cases, and other inappropriateness in 2 cases.Conclusions Inappropriate use of PPIs including mismatched indications and unsuitable usage and dosage occurs frequently in the hospital. It is suggested to take rectification measures, through multidepartment interaction and drug intervention, to regulate the application of PPIs in chemotherapy for breast cancer patients.
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