| 王成双,宋梅,邹鹏程,等.宫颈癌鼻转移 1例报告并文献复习[J].安徽医药,2021,25(10):2085-2087. |
| 宫颈癌鼻转移 1例报告并文献复习 |
| Nasal metastasis of cervical cancer: a case report |
| |
| DOI：10.3969/j.issn.1009-6469.2021.10.041 |
| 中文关键词: 子宫肿瘤 抗原， CD34 角蛋白 7 鼻转移 病例报告 文献复习 |
| 英文关键词: Uterine neoplasms Antigens, CD34 Keratin-7 Nasal metastasis Case report Literatures review |
| 基金项目: |
|
| 摘要点击次数: 1235 |
| 全文下载次数: 404 |
| 中文摘要: |
| 目的结合文献报告 1例宫颈癌鼻转移病例。方法对青岛市中心医院 2018年 3月 22日至 2018年 9月 4日收治的 1例年轻女性宫颈癌鼻转移病例进行报道并对文献复习。结果女， 37岁，以阴道不规则出血 1月收入院。妇科检查及彩超检查示宫颈肿物。予以行宫颈活检。病理示(宫颈)鳞状细胞癌，脉管内查见癌栓。免疫组化结果: CD34(血管 +)，D2-40(脉管+)。予以行同步放化疗，治疗过程中出现鼻部肿物，行鼻部肿物活检病理示:鳞状细胞癌，结合病史考虑宫颈源性鳞癌转移。免疫组化结果为抑癌基因 P16(+)、 P40(+)、 P63(+)，角蛋白 7(CK7)(?)。予以行放疗，效果差，病人半年内死亡。结论宫颈癌病人，鼻转移罕见，放疗效果差，病例病情进展迅速，预后差。需要加强此类病例资料收集。 |
| 英文摘要: |
| Objective To report the clinical observation about a case of nasal metastasis of cervical cancer and review literature. Methods A case of nasal metastasis of cervical cancer in a young woman admitted to Qingdao Central Hospital from March 22, 2018to September 4, 2018 was reported and the literature was reviewed.Results A 37-year-old female was admitted into Qingdao CentralHospital in complaint of Irregular vaginal bleeding for 1 month.Gynecological examination and color Doppler ultrasonography showedcervical mass. Cervical biopsy was performed to identify the mass, pathological and immunohistochemical examination showed that (cervix) squamous cell carcinoma, intravascular thrombus found, CD34(+), D2-40 (+). Nasal mass was found during concurrent radiotherapy and chemotherapy. Biopsy of nasal neoplasms showed that squamous cell carcinoma, immunohistochemical examination showed thatP16 (+) P40 (+) P63 (+) CK7 (?), and the diagnosis of nasal metastasis of cervical cancer was established based on medical history. Thepatient was insensitive to radiotherapy and died within six months.Conclusion Nasal metastasis is rare in patients with cervical cancer. Such disease develop rapidly with poor prognosis.More attention should be paid on the collection of associated clinical data. |
|
查看全文
查看/发表评论 下载PDF阅读器 |
| 关闭 |
