| 吴秋惠,王鸯鸯,陈皓然,等.稳定期慢性阻塞性肺疾病病人生存质量影响因素分析[J].安徽医药,2021,25(12):2387-2390. |
| 稳定期慢性阻塞性肺疾病病人生存质量影响因素分析 |
| Influencing factors for quality of life in patients with chronic obstructive pulmonary disease at stable stage |
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| DOI：10.3969/j.issn.1009-6469.2021.12.013 |
| 中文关键词: 肺疾病，慢性阻塞性 服药依从性 生存质量 影响因素 调查和问卷 |
| 英文关键词: Pulmonary disease, chronic obstructive Medication adherence Quality of life Influencing factors Surveys and questionnaires |
| 基金项目:国家自然科学基金资助项目( 71704075) |
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| 中文摘要: |
| 目的探讨分析影响稳定期慢性阻塞性肺疾病( COPD)病人生存质量的因素并提出改进策略。方法选取 2019年 6 —7月在南京鼓楼医院药学门诊就诊的 COPD病人 120例，采用调查问卷方式收集其一般资料及 COPD评估测试( CAT)评分、 Morisky用药依从性问卷( MMAS-8)评分，通过欧洲五维健康量表计算健康效用值，对量表与因素进行单因素分析及多元线性回归分析。结果共发放 120份问卷，有效回收 115份，单因素分析结果显示用药种类越多［“≤2”比“3~5”比“>5”:(0.747±0.225)比( 0.733±0.178)比( 0.604±0.268)］、 CAT评分越高［“轻”比“中”比“严重”“非常严重”:(0.833±0.138)比( 0.753±0.168)比( 0.610±0.267)比( 0.536±0.220)］效用值越低( P<0.05)病人的生存质量越差；多元线性回归分析显示吸烟( β=.0.186)、 CAT评分( β=.0.009)、 =0.030)为 COPD病存质量的影响因素( P<0.05)。结论吸烟、 CAT评分为 COPD病人生存质量的危险因素， MMAS-8评分为其保护因素。药师可通过开设药物治疗管理门诊，帮助 COPD病人戒烟、提高疾病知而比MMAS-8评分(β，人生，识、解决药物相关问题等，从而改善病人生存质量。 |
| 英文摘要: |
| Objective To explore and analyze the factors affecting the quality of life of patients with chronic obstructive pulmonarydisease (COPD) and to put forward improvement strategies.Methods A total of 120 COPD patients treated in Pharmaceutical Outpa.tient Department of Nanjing Drum Tower Hospital from June to July in 2019 were selected for the study. The general data, COPD as.sessment test (CAT) score and Morisky medication adherence scale (MMAS-8) score were collected by questionnaire. The health utility value was calculated by European five-dimension health scale, and the scale and factors were analyzed by univariate analysis and multi. ple linear regression analysis.Results A total of 120 questionnaires were distributed and 115 were effectively recovered. The resultsof univariate analysis showed that the more kinds of medication ["≤2" vs. "3-5" vs. ">5":(0.747±0.225) vs. (0.733±0.178) vs. (0.604± 0.268)], the higher CAT score ["mild" vs. "medium" vs. "serious" vs. "most serious": (0.833±0.138) vs. (0.753±0.168) vs. (0.610±0.267) vs. (0.536±0.220)], the lower the utility value (P<0.05), and the worse quality of life of the patients. Multiple linear regression analysis results showed that smoking (β=.0.186), CAT score (β=.0.009), MMAS-8 score (β= 0.030) were the influencing factors for quality of life in patients with COPD (P < 0.05).Conclusions Smoking and CAT score are the risk factors for quality of life in patients with COPD, and MMAS-8 score is the protective factor. Pharmacists can help COPD patients quit smoking, improve disease knowledge and solve medication-related problems by setting up medication therapy management (MTM) clinics, so as to improve the quality of life of COPD patients. |
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