| 滕沁伶,刘章英,贺晓春.呼吸机无创高频振荡通气在极低出生体质量儿呼吸窘迫综合征 42例中的疗效分析[J].安徽医药,2022,26(1):172-175. |
| 呼吸机无创高频振荡通气在极低出生体质量儿呼吸窘迫综合征 42例中的疗效分析 |
| Efficacy analysis of non-invasive high frequency oscillatory ventilation with ventilator in 42 cases of very low birth weight infants with respiratory distress syndrome |
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| DOI：10.3969/j.issn.1009-6469.2022.01.040 |
| 中文关键词: 呼吸窘迫综合征，新生儿 无创通气 高频通气 连续气道正压通气 婴儿，极低出生体质量 |
| 英文关键词: Respiratory distress syndrome, newborn Noninvasive ventilation High-frequency ventilation Continuous positive airway pressure Infant, very low birth weight |
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| 中文摘要: |
| 目的探讨无创高频振荡通气在极低出生体质量儿呼吸窘迫综合征拔管撤机后的效果。方法选择 2017年 3月至 2019年 2月在四川省妇幼保健院接受有创呼吸支持超 48 h，并在出生 3周内撤机的极低出生体质量呼吸窘迫综合征病儿 85例进行回顾性分析。根据接受呼吸支持的不同将其分为两组，对照组 43例行经鼻持续气道正压通气( NCPAP)，观察组 42例行经鼻无创高频振荡通气模式( NHFOV)。对比两组 7d内撤机成功率、血气分析指标、一般情况、并发症发生情况。结果观察组 7d内撤机成功率为 83.72%，明显高于对照组的 65.12%(P<0.05)。两组二氧化碳分压( PaCO2)水平均明显下降，但观察组下降幅度更大，两组氧分压( PaO2)及氧分压 /吸氧分数( FiO2)水平均明显升高，但观察组升高更明显( P<0.05)。两组总辅助通气时间对比差异无统计学意义( P>0.05)但观察组开奶时间及全肠喂养时间均明显较对照组短( P<0.05)。对照组共出现 14例 |
| 英文摘要: |
| Objective To investigate the effect of non-invasive high frequency oscillatory ventilation (NHFOSV) on very low birthweight infants with respiratory distress syndrome after extubation.Methods A retrospective analysis of 85 children with very low birthweight respiratory distress syndrome who underwent invasive respiratory support for 48 hours and withdrawn within 3 weeks of birth inSichuan Maternal and Child Health Hospital from March 2017 to February 2019 was performed. According to the children's respiratorysupport, they were divided into two groups. The control group underwent nasal continuous positive airway pressure (NCPAP), and theobservation group underwent NHFOV. The success rate of 7d weaning, blood gas analysis index, general condition and complicationswere compared between the two groups.Results The success rate of 7d weaning in the observation group was 83.72%, which was sig-nificantly higher than that in the control group (65.12%) (P<0.05).The Partial Pressure of Carbon Dioxide(PaCO2)levels in the twogroups were significantly decreased, but the decrease was greater in the observation group. The Partial Pressure Of Oxygen(PaO2)andPaO2/FiO2 levels were significantly increased in the two groups, but the increase in the observation group was more significant (P< 0.05). There was no significant difference in the total assisted ventilation time between the two groups (P>0.05), but the observation time and the total feeding time were significantly shorter in the observation group than in the control group (P<0.05). There were 14 cas-es (33.33%) of complications in the control group, and the difference was statistically significant in 5 cases (11.63%) in the observationgroup (P<0.05).Conclusion NHFOV can significantly improve the success rate of extubation and weaning of very low birth weight in-fants with respiratory distress syndrome, improve the blood gas analysis index, shorten the time of opening milk and whole intestinefeeding, and reduce the incidence of complications compared with NCPAP. |
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