| 杨洋,高广周,张晓明,等.保定地区急性胰腺炎 1 424例病因分析[J].安徽医药,2022,26(6):1151-1154. |
| 保定地区急性胰腺炎 1 424例病因分析 |
| Acute pancreatitis in Baoding region: an etiological analysis of 1 424 cases |
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| DOI：10.3969/j.issn.1009-6469.2022.06.021 |
| 中文关键词: 胰腺炎 危险因素 影响因素分析 保定地区 病因 年龄 性别 疾病严重程度 |
| 英文关键词: Pancreatitis Risk factors Root cause analysis Baoding area Etiology Age Gender Severity |
| 基金项目:中国肝炎防治基金会—天晴肝病研究基金( TQGB20170148) |
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| 中文摘要: |
| 目的探讨保定地区急性胰腺炎( AP)病人的病因及其与性别、年龄、疾病严重程度的关系。方法回顾性纳入 2011年 1月至 2020年 12月保定市第一中心医院收治的 AP病人共 1 424例，采集性别、年龄、疾病严重程度等临床信息，归纳 AP病因，并对不同时间段、性别、年龄段及严重程度的病因分布情况进行分析。结果病例 1 424例中胆源性 AP 765例( 53.7%)、高三酰甘油血症性 AP 329例( 23.1%)、特发性 AP 168例( 11.8%)、酒精性 AP 100例( 7.0%)、其他病因 62例( 4.4%)。 2011—2015年和 2016—2020年两个时间段内 AP病因构成比顺序从高到低均为胆源性、高三酰甘油血症性、特发性、酒精性、其他病因，差异无统计学意义( P>0.05)。女性胆源性 AP比例高于男性( 66.1%比 45.5%)(P<0.01)。男性高三酰甘油血症性 AP、酒精性 AP比例高于女性( 26.3%比 18.3%，11.6%比 0.2%)(均 P<0.01)。老年组胆源性 AP的比例高于低龄组和中年组( 82.5%比 26.7%、 37%)(均 P<0.016)。中年组高三酰甘油血症性 AP、酒精性 AP的比例均高于老年组( 36.3%比 1.7%、9.8%比 2.7%)(均 P< |
| 英文摘要: |
| Objective To investigate the etiology of acute pancreatitis (AP) in Baoding region and its correlation with gender, ageand severity of the disease.Methods A total of 1 424 patients with AP admitted to The First Central Hospital of Baoding in HebeiProvince from January 2011 to December 2020 were retrospectively included. The clinical data were collected including gender, ageand severity of the disease and the etiology of AP was summarized. The etiological distribution of different times, gender, age and the severity of AP was analyzed.Results Of 1 424 patients with AP there were 765 (53.7%) cases of biliary AP,329 (23.1%) cases of hypertriglyceridemic AP,168 (11.8%) casesof idiopathic AP, 100 (7%) casesof alcoholic AP and 62 (4.4%) cases of AP from other causes.Biliary factor was the most common cause of AP in the periods of 2011 to 2015 and 2016 to 2020, followed by hypertriglyceridemic, idiopathic, alcoholic and other causes; there was no statistically significant difference in the etiological distribution between these two periods (P>0.05). The proportion of biliary AP in female patients was higher than that in male patients(66.1% vs. 45.5%, P<0.01). Theproportions of hypertriglyceridemic AP, alcoholic AP in male patients were higher than those in female patients (26.3% vs. 18.3%, 11.6% vs. 0.2%, respectively; both P<0.01). The proportion of biliary AP in old age group was higher than those in younger age group and middle age group (82.5% vs. 26.7%, 37%, respectively; both P<0.016). The proportions of hypertriglyceridemic AP and alcoholicAP in middle age group were higher than that in old age group (36.3% vs. 1.7%, 9.8% vs. 2.7%; both P<0.01). The proportion of idiopathic AP in younger age group was higher than those in middle age group and old age group (53.3% vs. 14.0%, 6.8%, respectively; both P<0.016). The proportions of hypertriglyceridemic APin moderately severe acute pancreatitis (MSAP) patients and severe acutepancreatitis (SAP) were higher than that in mild acute pancreatitis (MAP) (32.2% vs. 15.8%, 33.3% vs. 15.8%;both P<0.016). The proportion of idiopathic AP in MAP patients was higher than those in MSAP patients and SAP patients (15.0% vs. 8.3%, 4.0%, respectively; both P<0.016).Conclusions In Baoding region of Hebei province, biliary AP and hypertriglyceridemic AP ranked respectively thefirst and second causes. Most of the patients with biliary acute pancreatitis are females,while hypertriglyceridemic AP are more com mon in males and middle-aged patients. Hypertriglyceridemic AP tends to be severer,and are easily found in MSAP and SAP patients. |
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