| Objective Based on the analysis of formulas for treating heart diseases in Treatise on Febrile Diseases and Synopsis ofthe Golden Chamber, this paper probes into the medication rules of Zhongjing in treating heart diseases.Methods Excel 2016 was used to establish a database for prescription conforming to the standard, and frequency analysis was conducted for drug properties, drugtaste, drug classification, etc. And correlation degree and cluster analysis was performed with IBM SPSS Modeler 18.0 and IBM SPSS Statistics Version 26.0.Results A total of 51 prescriptions were included in this study, involving 49 kinds of traditional Chinese medicine, among which the frequently used drugs were Licorice, Ramulus Cinnamomi, Ginger, etc. Twenty association rules were obtained,including 3 binomial association rules, such as "Ginger, Jujube"; 14 three association rules such as "Ginger, Ginseng + Jujube"; and 3four association rules, such as "Licorice, Jujube + Ginger + Ramulus Cinnamomi". Cluster analysis showed that there were 9 groups, including 4 single drug groups, such as "Trichosanthes kirilowii Maxim", "Peony" etc. Five drug pairs were combined, such as "Pinellia ternata+Radix Scutellariae", "Poria cocos+Atractylodes" etc. As can be seen from the network link network diagram, "Ramulus Cinnamomi-Licorice", "Ginger-Jujube" and so on have strong network link relationship, the high-frequency drug pair showed that "Ramulus Cinnamomi-Licorice" was the most frequently used drug pair.Conclusion Zhang Zhongjing's treatment of cardiovascular diseases focuses more on warming the heart, smoothing the liver and strengthening and spleen, harmonizing the body and protecting the spleenand stomach. |
