| 祁旺,黄磊,卞海林,等.急性胰腺炎 356例抗菌药物使用情况调查[J].安徽医药,2022,26(7):1470-1473. |
| 急性胰腺炎 356例抗菌药物使用情况调查 |
| Investigation of the use of antibiotics in 356 cases of acute pancreatitis |
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| DOI：10.3969/j.issn.1009-6469.2022.07.046 |
| 中文关键词: 胰腺炎 处方不当 抗菌药 莫西沙星 奥硝唑 头孢他啶 |
| 英文关键词: Pancreatitis Inappropriate prescription Antibiotics Moxifloxacin Ornidazole Ceftazidime |
| 基金项目: |
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| 中文摘要: |
| 目的调查分析急性胰腺炎( AP)病人的抗菌药物使用情况，提高 AP抗感染治疗水平。方法采用回顾性研究方法，利用 HIS系统及电子病历系统收集盐城市第一人民医院消化科 2019年 1—12月收治的 356例 AP病人的基本信息，针对抗菌药物使用情况进行统计，对其使用合理性进行分析评价。结果 356例 AP病人有 348例( 97.75%)使用了抗菌药物，使用例次排名前三的抗菌药物分别为莫西沙星 169例( 28.64%)、奥硝唑 136例( 23.05%)、头孢他啶 112例( 18.98%)；初始治疗方案中抗菌药物联合使用有 203例( 57.02%)更换抗菌药物治疗方案的有 30例( 8.42%)；共存在 209例次用药不适宜情况，主要为无指征预防用抗菌药物 158例( 75.60%)。，结论抗菌药物在 AP病人的应用中仍存在诸多不合理情况，应加强对临床医师的宣教及 |
| 英文摘要: |
| Objective To investigate and analyze the use of antibiotics in patients with acute pancreatitis (AP) to improve the effect of anti-infective therapy for AP.Methods A retrospective research method was used to collect the basic information of 356 AP pa-tients admitted to the Department of Gastroenterology, The First People's Hospital of Yancheng City, from January to December 2019by using the HIS system and electronic medical record system. Statistics on the use of antibiotics and analysis and evaluation of the ra-tionality of their use.Results Among the 356 AP patients, 348 (97.75%) used antibiotics, and the top 3 antibiotics were moxifloxacin(169 cases, 28.64%), ornidazole (136 cases, 23.05%) and ceftazidime (112 cases, 18.98%). In the initial therapeutic regimen, 203 cases(57.02%) were used in combination with antibiotics, and 30 cases (8.42%) were replaced by an antibiotic therapeutic regimen. Therewere 209 cases of unsuitable drug use, mainly 158 cases (75.60%) of unindicated prophylactic antibiotics.Conclusions There are still many unreasonable situations in the application of antibacterial drugs in AP patients, and the education and training of cliniciansshould be strengthened to promote rational use. |
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