| 程明琨,王明,段长恩,等.慢性阻塞性肺疾病急性加重病人发生肺栓塞的危险因素及 Caprini血栓风险评估量表的应用研究[J].安徽医药,2022,26(12):2508-2511. |
| 慢性阻塞性肺疾病急性加重病人发生肺栓塞的危险因素及 Caprini血栓风险评估量表的应用研究 |
| Risk factors for pulmonary embolism in patients with acute exacerbations of chronic obstructive pulmonary disease and application of Caprini risk assessment scale |
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| DOI：10.3969/j.issn.1009-6469.2022.12.038 |
| 中文关键词: 肺疾病，慢性阻塞性 肺栓塞 嘧啶二聚物 调查和问卷 Caprini血栓风险评估量表 危险因素 |
| 英文关键词: Pulmonary disease, chronic obstructive Pulmonary embolism Pyrimidine dimers Surveys and questionnaires Caprini risk assessment scale Risk factors |
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| 中文摘要: |
| 目的探讨慢性阻塞性肺疾病急性加重( AECOPD)病人发生肺栓塞的危险因素及 Caprini血栓风险评估量表的应用效果。方法选择新乡医学院第一附属医院 2018年 3月至 2019年 2月 AECOPD 153例作为研究对象，收集病人的临床资料，统计肺栓塞发生情况并通过统计学分析其危险因素。所有研究对象按照是否应用 Caprini血栓风险评估量表分为两组，未评估组入院后常规临床干预，评估组接受 Caprini血栓风险评估量表评估并以此结果为指导的临床干预，比较两组的肺栓塞发生情况。结果研究中 153例 AECOPD病人发生肺栓塞 30例，发生率为 19.6%。单因素提示体质量指数(BMI)≥25 kg/m2有糖尿病史、既往静脉血栓史、有下肢水肿、卧床时间 ≥7 d、血二氧化碳分压 ≤36 mmHg、D-二聚体 ≥500 μg/L、慢性阻塞性肺疾病(、COPD)分级 >Ⅱ级的病人肺栓塞发生率更高，分别为 27.5%(22/80)、 34.1%(14/41)、 42.9%(9/21)、 44.1%(15/34)、 27.1%(23/85)、 36.0%(18/50)、 30.6%(19/62)、 28.0%(21/75)，与无以上因素的病人肺栓塞发生率 11.0%(8/73)、 14.3%(16/112)、 15.9%(21/132)、 |
| 英文摘要: |
| Objective To investigate the risk factors for pulmonary embolism in patients with acute exacerbations of chronic obstruc.tive pulmonary disease and application of Caprini risk assessment scale.Methods A total of 153 patients with acute exacerbations ofchronic obstructive pulmonary disease from March 2018 to February 2019 in our hospital were selected as subjects, the clinical data ofpatients were collected, and the occurrence of pulmonary embolism was counted and the risk factors were statistically analyzed. All sub.jects were divided into two groups according to whether the Caprini risk assessment scale was used, and the patients in unevaluatedgroup received routine clinical intervention after admission, the patients in evaluation group were evaluated by Caprini risk assessmentscale and the clinical intervention guided by this result, the occurrence of pulmonary embolism of two groups was compared.Results In 153 patients with acute exacerbations of chronic obstructive pulmonary disease, 30 cases developed pulmonary embolism, the inci.dence rate was 19.6%. Single factor indicated that body mass index ≥25 kg/m2, diabetes history, previous venous thrombosis history,lower extremity edema, bed time ≥7 d, blood carbon dioxide partial pressure ≤36 mmHg, D-dimer ≥500 μg/L, chronic obstructive pul.monary disease (COPD) classification > Ⅱ in patients has higher incidence rate of pulmonary embolism, 27.5% (22/80),34.1% (14/41), |
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