| 刘亦晴,邹华伟,丁华.环乳晕切口入路保留乳头乳晕复合体的乳房切除术联合即刻乳房重建对乳腺癌病人乳腺美观性、应激反应指标的影响[J].安徽医药,2024,28(2):348-351. |
| 环乳晕切口入路保留乳头乳晕复合体的乳房切除术联合即刻乳房重建对乳腺癌病人乳腺美观性、应激反应指标的影响 |
| Effects of NSM via circular areola incision approach combined with immediate breast reconstruction on breast aesthetics and stress response indicators in patients with breast cancer |
| |
| DOI：10.3969/j.issn.1009-6469.2024.02.030 |
| 中文关键词: 乳腺肿瘤 环乳晕切 NSM 即刻乳房重建 应激反应 |
| 英文关键词: Breast neoplasms Circular areola incision NSM Immediate breast reconstruction Stress response |
| 基金项目: |
|
| 摘要点击次数: 286 |
| 全文下载次数: 167 |
| 中文摘要: |
| 目的探讨环乳晕切口入路保留乳头乳晕复合体的乳房切除术(NSM)联合即刻乳房重建对乳腺癌病人乳腺美观性、应激反应指标的影响。方法选取 2017年 8月至 2020年 8月周口市中心医院收治的 93例乳腺癌病人，采用随机数字表法分为两组，对照组 46例采用放射状切口手术治疗，观察组 47例采用环乳晕切口入路 NSM联合即刻乳房重建治疗，比较两组病人围手术期指标、手术并发症发生情况、乳腺美观性指标、应激反应指标［超氧化物歧化酶( SOD)、晚期氧化蛋白产物( AOPP)、皮质醇( Cor)］变化。结果观察组手术时间为( 132.48±15.69)min，显著大于对照组( P<0.05)住院时间为( 7.41±0.83)d，显著小于对照组( P<0.05)；两组病人手术切口感染、皮瓣积液、乳头凹陷、切口愈合不良等并发症发生，情况差异无统计学意义( P>0.05)，但观察组手术并发症总发生率为 2.13%，显著低于对照组的 17.39%(P<0.05)；观察组病人术后 7d切口瘢痕、乳房外形、双乳对称性、整体美学效果评分分别为( 3.26±0.33)分、(3.94±0.41)分、(3.33±0.34)分、(4.05±0.41)分，术后 1个月评分分别为( 3.85±0.34)分、(4.19±0.27)分、(3.86±0.25)分、(4.28±0.19)分，均显著高于对照组( P<0.05)。术后观察组 SOD水平为( 73.40±7.35)U/ mL，显著高于对照组( P<0.05)， AOPP、Cor水平分别为( 11.03±1.05)μmol/L、(192.78±19.34)nmol/L，显著均低于对照组( P<0.05)。结论环乳晕切口入路 NSM联合即刻乳房重建治疗乳腺癌病人可有效减少手术并发症的发生，提高病人乳腺美观性，缓解应激反应指标的变化。 |
| 英文摘要: |
| Objective To investigate the effects of nipple-areola complex sparing mastectomy (NSM) via circular areola incision ap.proach combined with immediate breast reconstruction on breast aesthetics and stress response indicators in patients with breast cancer.Methods A total of 93 patients with breast cancer treated in the Zhoukou Central Hospital between August 2017 and August 2020were selected as the research subjects and were randomly divided into two groups. Forty-six cases in the control group were treated withradial incision approach surgery, and 47 cases in the observation group were given circular areola incision approach NSM combinedwith immediate breast reconstruction. The perioperative indicators, occurrence of surgical complications, breast aesthetics indicatorsand stress response indicators [superoxide dismutase (SOD), advanced oxidation protein product (AOPP), cortisol (Cor)] between thetwo groups were compared.Results The surgical time of observation group was (132.48±15.69) min, which was significantly longer than that of control group (P<0.05); the hospital stay was (7.41±0.83) d, which was significantly shorter than that of control group (P< 0.05). There were no significant differences in the occurrence of complications such as surgical incision infection, valve effusion, nippledepression and poor incision healing between the two groups (P>0.05), but the total incidence of surgical complications in the observa.tion group (2.13%) was significantly lower than that in the control group (17.39%) (P<0.05). The scores of incision scar, breast shape, breast symmetry and overall aesthetic effect in observation group were (3.26±0.33) points, (3.94±0.41) points, (3.33±0.34) points and(4.05±0.41) points at 7 days after surgery and (3.85±0.34) points, (4.19±0.27) points, (3.86±0.25) points and (4.28±0.19) points at 1month after surgery, which were significantly higher than those of the control group (P<0.05). The SOD level of observation group was (73.40±7.35) U/mL after surgery, significantly higher than that of control group (P<0.05) while the levels of AOPP and Cor (11.03±1.05) μmol/L and (192.78±19.34) nmol/L were significantly lower than those of control group after surgery (P<0.05). Conclusion NSM via circular areola incision approach combined with immediate breast reconstruction for patients with breast cancer can effective.ly reduce the occurrence of surgical complications, improve the breast aesthetics, and alleviate changes in stress response indicators. |
|
查看全文
查看/发表评论 下载PDF阅读器 |
| 关闭 |
|
|
|
