| 颜谈,许静,汝宁,等.以急性多发性脑梗死为主要表现的特鲁索综合征 3例[J].安徽医药,2024,28(2):386-389. |
| 以急性多发性脑梗死为主要表现的特鲁索综合征 3例 |
| Three cases of Trousseau's syndrome with acute multiple cerebral infarction as the main manifestation |
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| DOI：10.3969/j.issn.1009-6469.2024.02.039 |
| 中文关键词: 副肿瘤综合征，神经系统 栓塞和血栓形成 特鲁索综合征 脑梗死 三流域征 恶性肿瘤 |
| 英文关键词: Paraneoplastic syndromes, nervous system Embolism and thrombosis Trousseau's syndrome Cerebral infarction Threeterritory sign Malignanttumor |
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| 中文摘要: |
| 目的分析以急性多发性脑梗死为主要表现的特鲁索综合征( Trousseau's syndrome，TS)的临床及影像学特征。方法回顾分析 2019年 12月至 2021年 12月阜阳市人民医院神经内科收治的 3例以急性多发性脑梗死为主要表现的 TS病人的临床资料，并结合相关文献分析该病的临床和影像特征。结果其中男 1例，女 2例；发病年龄范围为 52~85岁； 3例病人 D-二聚体均明显升高；头颅 MRI均显示为以“三流域征”为特点的急性多发性脑梗死；伴腹腔转移瘤 1例，伴静脉系统血栓 2例； 1例予低分子肝素抗凝 +双抗抗血小板聚集， 2例予低分子肝素抗凝治疗。结论急性多发性脑梗死是 TS的一个重要表现；对于不符合血管分布的急性多发性脑梗死，病因需考虑恶性肿瘤所致高凝状态可能； D-D是诊断 TS的重要线索。 |
| 英文摘要: |
| Objective To analyze the clinical and imaging features ofTrousseau'ssyndromemanifested as acute multiple cerebral in. farction.Methods The clinical data of 3 patients with Trousseau's syndrome presenting as acute multiple cerebral infarction admittedto the Department of Neurology the People's Hospital of Fuyang from December 2019 to December 2021 were retrospectively analyzed,and the clinical and imaging characteristics of the disease were analyzed in combination with related literature.Results Of the 3 pa. tients,2were female and the other wasmale;The age of onset ranged from 52 to 85 years old;D-dimer level was significantly elevated inall 3 patients; cranial MRI of all of the 3 patients showed multiple cerebral infarction,1 case with abdominal metastasis;2 cases withthrombosis of the venous system;1 case received anticoagulant and antiplatelet therapy.Two patients received anticoagulation therapyoflow molecular weight heparin.Conclusions An important manifestation of Trousseau'ssyndrome is acute multiple cerebral infarc.tion. Hypercoagulability caused by malignant tumor should be considered as the etiology of multiple acute cerebral infarction that doesnot conform to vascular distribution. D-dimer is an important clue in the diagnosis of Trousseau's syndrome. |
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