| 秦泽辉,田行瀚.金黄色葡萄球菌血流感染预后的研究进展[J].安徽医药,待发表. |
| 金黄色葡萄球菌血流感染预后的研究进展 |
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| 投稿时间：2024-04-02 录用日期：2024-04-18 |
| DOI： |
| 中文关键词: 金黄色葡萄球菌 血流感染 预后 |
| 英文关键词: |
| 基金项目:山东省医药卫生科技发展计划项目(编号：2019WS281) |
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| 摘要点击次数: 120 |
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| 中文摘要: |
| 金黄色葡萄球菌是院内获得性感染的主要病原体之一,当它侵入血液系统时,就会导致金黄色葡萄球菌血流感染(Staphylococcus aureus bloodstream infection,SABI)。SABI常见的预后相关因素包括：性别、是否有基础疾病与SABI的预后关系密切；年龄也是影响预后的独立危险因素；感染耐甲氧西林金黄色葡萄球菌(methicillin resistant staphylococcus aureus,MRSA)患者预后差,而且不同感染部位导致的血流感染预后情况也不同；SABI患者血清白细胞介素-10值越高患者预后越差；最后患者接受治疗情况等都对患者预后有影响。分析SABI预后相关因素并建立评估预后的预测模型,可以帮助临床医生制定最佳的治疗方案和监护措施。 |
| 英文摘要: |
| Staphylococcus aureus, notably the methicillin-resistant strain (MRSA), stands as a predominant causative agent for hospital-acquired infections. Its intrusion into the bloodstream precipitates Staphylococcus aureus bloodstream infection (SABI), a condition of considerable clinical consequence. Pertinent prognostic factors in SABI encompass gender, the presence of underlying medical conditions, and age, the latter being an independent risk determinant influencing overall outcomes. Patients afflicted with MRSA exhibit a notably compromised prognosis. Furthermore, diverse infection sites contribute to varying prognostic scenarios in SABI. Elevated serum levels of interleukin-10 in SABI patients correlate with a deterioration in prognosis. The treatment regimen administered to patients emerges as a pivotal factor influencing overall prognostic outcomes. An in-depth analysis of prognostic determinants in SABI and the establishment of predictive models serve to empower clinical practitioners in formulating optimal therapeutic strategies and monitoring protocols. |
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