| Objective To investigate the prognostic value of neutrophil-to-lymphocyte ratio (NLR) in patients with suspected infection and qSOFA (quick sequential organ failure assessment) =1 in emergency department. Methods Patients with suspected infection and qSOFA=1 in the emergency department were enrolled from MIMIC-Ⅳ database and divided into group A (ideological change), group B (systolic blood pressure ≤100 mmHg), and group C (respiratory rate ≥22 times /min). The risk of poor prognosis between high NLR and low NLR was compared. Main poor prognosis for 28 d death, secondary poor prognosis for 72 h in intensive technical support, including the use of the breathing machine, and using vessel vasopressors and RRT (renal replacement therapy). Results Logistic regression analysis, group B, NLR is 28 d of death the independent factors (OR = 1.023, P < 0.001); Group A and group C, NLR of 28 d death independent factors (P > 0.05). Group B, NLR average of 8.0 (4.0 15.0). Cox proportional hazards regression analysis showed that in group B, the risk of death in NLR≥15 group was higher than that in NLR < 15 group (HR=1.685, P=0.015). NLR acuity 4 and NLR < 4 death risk difference between no statistical significance (P > 0.05). In group B, for patients with hospitalization time ≥72 hours and NLR≥15, the risk of receiving critical technical support at 72 hours was higher than that of NLR < 15 (ventilator, HR=1.820, P=0.005; Vasopressor use, HR=1.912, P < 0.001; RRT, HR=2.380, P=0.013). Conclusions NLR may apply to emergency suspected infection with qSOFA = 1 (systolic blood pressure, 100 mmHg) or less) prognostic assessment. |
