| 吴静鸣,黄晓青,曹阳,等.柴葛解肌颗粒醇沉工艺对石膏成分保留及解热作用的影响[J].安徽医药,2020,24(7):1295-1297. |
| 柴葛解肌颗粒醇沉工艺对石膏成分保留及解热作用的影响 |
| Study on the effects of alcohol precipitation process of Chaige Jieji granules on the retention of Gypsum Fibrosum components and antipyretic effect |
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| DOI：10.3969/j.issn.1009?6469.2020.07.006 |
| 中文关键词: 中药工艺改进 柴葛解肌汤 石膏 硫酸钙 解肌清热 醇沉工艺 |
| 英文关键词: Technology improving(TCD) Chaige Jieji decoction Gypsum fibrosum Calcium sulfate Reliev muscle clear heat Alcohol precipitation proces |
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| 摘要点击次数: 2766 |
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| 中文摘要: |
| 目的通过研究石膏成分保留及解热作用，探讨柴葛解肌颗粒醇沉工艺合理性。方法采用络合滴定法测定柴葛解肌颗粒醇沉前后浸膏中含水硫酸钙含量，采用 2，4?二硝基苯酚致大鼠发热模型、内毒素致家兔发热模型，对其解热药效作用进行对比研究。结果醇沉前后浸膏均具有一定的解热作用，且与阳性药组比较，三者差异无统计学意义。结论柴葛解肌颗粒醇沉工艺合理。 |
| 英文摘要: |
| Objective The rationality of alcohol precipitation process of Chaige Jieji granules was discussed by studying the reten? tion of Gypsum Fibrosum components and antipyretic effect.Methods The study determined the content of CaSO4·2H2O in the ex? tracts of Chaige Jieji granules before and after alcohol precipitation by complexometric titration，and used fever models induced by 2，4?dinitrophenol in rats and by endotoxin in rabbits to compare their antipyretic effects.Results The extracts both had antipyret? ic effect.Compared with positive drug group，there was no significant difference between the three groups.Conclusion The alcohol precipitation process is reasonable and feasible. |
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