| 吴静鸣,黄晓青,曹阳,等.正交试验优化参白散结颗粒的水提工艺[J].安徽医药,2020,24(11):2139-2142. |
| 正交试验优化参白散结颗粒的水提工艺 |
| Optimization of water extraction process for Shenbai Sanjie granules by orthogonal test |
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| DOI：10.3969/j.issn.1009?6469.2020.11.005 |
| 中文关键词: 中草药/分离和提纯 颗粒物 党参 白芍 参白散结颗粒 正交设计 高效液相色谱法 芍药苷 |
| 英文关键词: Drugs,Chinese herbal/isolation & purification Particulate matter Codonopsis pilosula Radix paeoniae alba Shenbai sanjie granules Orthogonal test HPLC Paeoniflorin |
| 基金项目: |
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| 中文摘要: |
| 目的优选参白散结颗粒的最佳水提工艺。方法党参等九味药材合煎，分别采用正交设计，以浸膏得率和芍药苷含量为考察指标，优选最佳水提工艺条件。结果参白散结颗粒水提最佳工艺条件:党参等九味药材加入 10倍量水，煎煮 3次，每次 2h。结论优选出的提取工艺稳定，主要有效成分转移率高，为参白散结颗粒的生产工艺提供试验依据。 |
| 英文摘要: |
| Objective To optimize the water extraction process of Shenbai Sanjie granules.Methods Taking the ratio of dry ex? tract yielding and the content of paeoniflorin as two main reference indexes，orthogonal design method was used to determine the op? timal water extraction process for Codonopsis pilosula(Franch.)Nannf.and other nine medicinal herbs.Results The optimum ex? traction condition was described as follow:ten times amount of water，decocting 3 times，2 hours each time.Conclusion The opti? mal extraction process is stable and has a high transfer rate of active ingredient，and it could provide experimental basis for the production process of Shenbai Sanjie granules. |
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