文章摘要
符俊达,朱海萍,贾娜,等.瞳孔直径不同对青少年近视发展的影响[J].安徽医药,2021,25(1):68-71.
瞳孔直径不同对青少年近视发展的影响
Effects of different pupil diameter on the development of adolescent myopia
  
DOI:10.3969/j.issn.1009?6469.2021.01.017.
中文关键词: 近视  瞳孔直径  角膜塑形术  视网膜周边近视性离焦  眼轴  青少年
英文关键词: Myopia  Pupil diameter  Orthokeratologic procedures  Retinal periphery myopic defocus  Eye axis  Adolescent
基金项目:秦皇岛市科学技术研究与发展计划项目(201703A202)
作者单位E-mail
符俊达 秦皇岛市第一医院眼科河北秦皇岛 066000  
朱海萍 秦皇岛市第一医院眼科河北秦皇岛 066000  
贾娜 秦皇岛市第一医院眼科河北秦皇岛 066000  
王刚 秦皇岛市第一医院眼科河北秦皇岛 066000  
孙轶军 秦皇岛市第一医院眼科河北秦皇岛 066000 quz5193@163.com 
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中文摘要:
      目的研究不同瞳孔直径大小所致的视网膜周边离焦区别对青少年近视发展的影响。方法选取秦皇岛市第一医院 2016年 7月至 2017年 7月期间门诊收治的 8~12岁青少年低中度近视病人 200例 200眼,均进行屈光度、瞳孔直径、眼轴长度、角膜曲率等检测后,佩戴夜戴型角膜塑形镜,并进行为期 2年的随访,每 3个月随访 1次,详细记录屈光度、瞳孔直径、眼轴长度、角膜曲率等数据;根据不同光线下瞳孔直径大小分组,比较戴镜前后各组病人瞳孔直径大小变化量、屈光度增长量、眼轴增长量、角膜曲率改变量,并分析初始瞳孔直径与屈光度增长量、眼轴增长量、角膜曲率改变量之间的相关性。结果在不同光线条件下,瞳孔直径大于平均值病人的屈光度增长量为(-0.48±0.12)D、眼轴增长量为(0.79±0.14)mm,均要显著低于瞳孔直径小于平均值病人(P<0.05)角膜曲率改变量与瞳孔直径小于平均值病人相比差异无统计学意义(P>0.05);暗室条件下初始瞳孔直径与佩戴角膜塑形镜2,年后的屈光度增长量和眼轴增长量均呈负相关(r=-0.416 4、-0.512 3,P<0.001)与角膜曲率改变量无显著相关性(r=0.132 2,P>0.05);自然光条件下初始瞳孔直径与佩戴角膜塑形镜 2年后的屈光度增长量和,眼轴增长量均呈负相关(r=-0.417 0、-0.529 2,P<0.001),与角膜曲率改变量无显著相关性(r=-0.163 0,P>0.05)。结论瞳孔直径较大有利于角膜塑形镜对视网膜周边近视性离焦的干预,进而更好地控制近视发展进程。
英文摘要:
      Objective To study the effects of differences in retinal periphery defocus caused by different pupil diameter on thedevelopment of adolescent myopia.Methods A total of 200 adolescent patients(200 eyes)with low to moderate myopia aged 8 to12 years old who were admitted to outpatient of Qinhuangdao First Hospital from July 2016 to July 2017 were enrolled.All of themwere examined for diopter,pupil diameter,axial length and corneal curvature.Night?wearing orthokeratology was given to them.They were followed up for 2 years,once every 3 months.The diopter,pupil diameter,axial length,and corneal curvature were recorded in detail.According to different pupil diameter under different light,grouping was conducted.The changes in pupil diameter,diopter in? crement,axial increment,changes in corneal curvature before and after wearing glasses were compared among all groups.The corre?lation between initial pupil diameter and diopter increment,axial increment,changes in corneal curvature was analyzed.Results Under different light conditions,diopter increment and axial increment in patients with pupil diameter greater than mean valuewere -0.48±0.12D and 0.79±0.14mm,significantly lower than those with pupil diameter less than mean value(P<0.05).There was no significant difference in corneal curvature changes between the two kinds of patients(P>0.05).Under darkroom condition,ini? tial pupil diameter was negatively correlated with diopter increment at 2 years after wearing orthokeratology and axial increment(r=-0.416 4,-0.512 3,P<0.001),while not significantly correlated with corneal curvature changes(r=0.132 2,P>0.05).Under natural light condition,initial pupil diameter was negatively correlated with diopter increment at 2 years after wearing orthokeratolo? gy and axial increment(r=-0.417 0,-0.529 2,P<0.001),while not significantly correlated with corneal curvature changes(r= -0.163 0,P>0.05).Conclusion The larger pupil diameter is beneficial to intervention of orthokeratology on retinal periphery my? opic defocus,so as to better control the development of myopia.
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